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SMAPI Launcher: Is the 32-bit "Compatibility" Version Better?

Since the release of Stardew Valley 1.5.5, the game shifted its default framework from 32-bit XNA to 64-bit MonoGame. However, the developers maintain a for specific use cases:

The 32-bit environment often provides improved stability for older mods that may not be fully supported by 64-bit architectures, reducing potential crashes.

Systems with 4GB of RAM or less benefit from 32-bit applications, which naturally consume less memory baseline infrastructure than their 64-bit counterparts.