If the save continues to corrupt, you may need to disable the cloud temporarily. Right-click in your Steam Library. Select Properties > General . Toggle OFF "Enable Steam Cloud synchronization".

Go to your 221040\remote folder using the path listed above.

RE6 saves are located in a hidden folder. Knowing where these are is essential for backups or manual transfers.

Windows updates sometimes reset folder permissions. Re-apply Full Control to the 221040 folder (Method 4).