: The setup process will ask to format your virtual hard drive (Drive C:). Follow the prompts to let it create the necessary partitions.
With the VM configured, you are ready to install MS-DOS 6.22. It's a straightforward process. ms dos 622 img files works with virtual box top
Note: You will have to unmount/mount the next disk image when the setup asks for Disk 2, but it works like a charm. : The setup process will ask to format